Biological Engineering

Each year, tens of thousands of chemicals enter the market and ultimately the environment. While most of these compounds undergo safety testing before approval, their long-term effects on wildlife remain difficult to predict. To better estimate their potential threat for ecosystems, researchers at Eawag have explored biochemical signatures that indicate the level of chemical stress suffered by fish.

A new study by EPFL reveals that the notorious bacterial pathogen Pseudomonas aeruginosa must balance between effectively colonizing human airways and developing antibiotic tolerance to survive.

Results from a preclinical study in mice, led by EPFL, and a collaborative clinical study in patients show that the type 2 immune response – associated with parasitic infection and thought to play a negative role in cancer immunity – is positively correlated with long-term cancer remission.

Scientists at EPFL unveil DiffPALM, an innovative AI method that enhances the prediction of protein interactions and our understanding of biological processes potentially relevant to medical applications.

EPFL researchers have created a deep learning pipeline for designing soluble analogues of key protein structures used in pharmaceutical development, sidestepping the prohibitive cost of extracting these proteins from cell membranes.

In a new study, EPFL scientists have uncovered the complex genetic and environmental interactions influencing metabolic health and have validated their findings in actual human data.