Immerse yourself in the cytoskeleton

The name skeleton seems misleading – since the cytoskeleton is in fact not a rigid framework but rather a very dynamic structure. It not only ensures the cell’s mechanical stabilisation and external shape, but also plays a central role in transport within the cell as well as in cell division.

Of particular importance for cell division are the so-called microtubules. These tubular protein complexes are a significant component of the cytoskeleton. However, it is not only the healthy cells that they help to multiply; cancer cells and pathogens, for example, are also able to divide with the aid of the microtubules.

For this reason, researchers at PSI are using the large research facilities to find docking sites for new drugs. This could make it possible, for example, block the degradation of microtubules and prevent the division of diseased cells.

You can find out more about this topic in the issue of our magazine 5232 issue 3/2023.

Text: Paul Scherrer Institute/Benjamin A. Senn